| The Laryngoscope Cluster Analysis of Patients With Empty Nose Syndrome and Its Relation to Surgical Outcome Feb 26, 2026 Chia-Hsin Lu, Yun-Shien Lee, Pei-Wen Wu, Chi-Che Huang, Po-Hung Chang, Ta-Jen Lee, Chien-Chia Huang Patients with empty nose syndrome (ENS) present heterogeneous symptom patterns and varied surgical outcomes. This study aimed to stratify patients with ENS based on preoperative 25-item Sinonasal Outc... Journal Article |
| Plastic And Reconstructive Surgery. Global Open - Volume 14 Issue 2, Page e7466 Empty Nose Syndrome Treated With Inferior Turbinate Augmentation Using Homologous Costal Cartilage Feb 25, 2026 Yu-Hsun Chiu, Chung-Yu Hao, Yu-Xiang Kuo, Wei-Li Hung Empty nose syndrome (ENS) is a debilitating, iatrogenic condition caused by a previous inferior turbinectomy; the symptoms of which include subjective feelings of suffocation despite an objectively pa... Journal Article |
| The Laryngoscope Nasal Air-Jet Sensitivity Differentiates Empty Nose Syndrome and Turbinate Reduction Patients: A Pilot Study Jan 31, 2026 Kanghyun Kim, Ahmad Odeh, Jack Harness, Nidhi Jha, Veronica Formanek, Joseph Lee, Bradley Otto, Kathleen Kelly, Kai Zhao Abnormal nasal mucosal function has been frequently implicated in the symptomatology of empty nose syndrome (ENS), yet with limited evidence. This prospective pilot study aims to compare nasal mucosal... Journal Article |
| Journal Of Clinical Medicine - Volume 15 Issue 2 Validity and Reliability of a French Version of the Empty Nose Syndrome 6-Item Questionnaire Jan 19, 2026 Antonino Maniaci, Jérôme R Lechien To validate a French version of the Empty Nose Syndrome 6-Item Questionnaire (Fr-ENS6Q). Methods: Thirty-three patients with a diagnosis of empty nose syndrome (ENS) and 50 healthy individuals complet... Journal Article |
| Rhinology - Volume 63 Issue 6, Page 736-743 Serpentine Sign: evidence of airway compensation in patients with empty nose syndrome Dec 1, 2025 P-W Wu, F T-N Yu, T-J Lee, C-C Huang, P-H Chang, C-C Huang This study aimed to evaluate the presence of Serpentine Signs on computed tomography (CT) images and its impact on the clinical symptoms in patients with empty nose syndrome (ENS). METHODS: A retrospe... Journal Article |
 Journal Of Rhinology : Official Journal Of The Korean Rhinologic Society - Volume 32 Issue 3, Page 162-168Assessment of Autonomic Dysfunction in Patients With Empty Nose Syndrome Using the Composite Autonomic Symptom Scale-31 Nov 27, 2025 Sung Seok Ryu, Do Yeon Kim, Yong-ju Jang BACKGROUND AND OBJECTIVES: Empty nose syndrome (ENS) can occur as a consequence of aggressive turbinate surgery. However, some patients with similar surgical histories do not develop ENS, suggesting t... Journal Article |
 Journal Of Rhinology : Official Journal Of The Korean Rhinologic Society - Volume 32 Issue 3, Page 175-183Optimizing Human Nasal Turbinate Stem Cell Dosage for the Effective Treatment of Empty Nose Syndrome Nov 27, 2025 Yun Jin Kang, Dan Bi Park, David W Jang, Mi Hyun Lim, Jae Yoon Lee, Seung Yeon Yoo, Sung Won Kim, Do Hyun Kim BACKGROUND AND OBJECTIVES: Empty nose syndrome (ENS) is a chronic and debilitating condition characterized by atrophic nasal mucosa and impaired mucosal function, resulting in persistent nasal discomf... Journal Article |
 A Physiological Explanation of Stress, Air Hunger and Autonomic DysregulationNov 20, 2025 ENS disrupts multiple interlinked systems — nasal mechanics and sensation, lung reflexes, CO? balance, baroreflex function, cardiac rhythm and higher brain regulation — producing a predictable physiol... Blog |
 Stanford UniversityPersonalized Sound Therapy Study for Empty Nose Syndrome Treatment Oct 3, 2025 Kai Zhao Stanford University researchers are conducting a groundbreaking clinical trial investigating acoustic resonance therapy (ART) for ENS Research |
 ENT IstambulThe Discrepancy Between Turbinate Size and Patient Complaints in Empty Nose Syndrome Sep 15, 2025 Murat Enöz Turbinate Volume May Be Large, but Functionally Decreased. The health of the outer mucosa of the turbinates is crucial. |
 ENTtodayPhysiological, Psychological, or Perhaps a Little of Both? Aug 5, 2025 Renée Bacher ENS represents one of the more complex conditions in otolaryngology, characterized by the paradoxical feeling of nasal obstruction despite objectively patent airways Webpage |
 International Forum Of Allergy & Rhinology - Volume 15 Issue 8, Page 881-883Concerns on Sleep Assessment Complexity and Nasal Resistance Effects in Empty Nose Syndrome Jul 11, 2025 Hsiang-An Hsueh, Ta-Jen Lee, Li-Pang Chuang, Chi-Che Huang, Yi-Wei Chen, Po-Hung Chang, Chia-Chen Wu, Ya-Cheng Tang, Chia-Hsiang Fu Journal Article |
 European Archives Of Oto-rhino-laryngology : Official Journal Of The European - Volume 282 Issue 12, Page 6037-6048Depression and anxiety in empty nose syndrome: A systematic review and Meta-analysis Jul 5, 2025 Anuja H Shah, Isabelle J Chau, Shaun A Nguyen, Alexander N Duffy, Zachary M Soler, Rodney J Schlosser BACKGROUND: Empty nose syndrome (ENS) is a condition characterized by a persistent feeling of nasal obstruction despite having a patent nasal airway. This study aims to understand prevalence of depres... Journal Article |
 Clinical And Experimental Otorhinolaryngology - Volume 19 Issue 1, Page 79-85Treatment Outcomes of the Inferior Meatus Augmentation Procedure With Autologous Costal Cartilage for Empty Nose Syndrome Jun 25, 2025 Jang Wook Gwak, Yong-ju Jang OBJECTIVE: Empty nose syndrome (ENS) is a rare postoperative complication arising from turbinate surgery. Here, we report our clinical experience and comprehensive analysis of the inferior meatus augm... Journal Article |
 International Forum Of Allergy & Rhinology - Volume 15 Issue 7, Page 761-762Subjective Sleep Gains in Empty Nose Syndrome: A Cautionary Note on the Need for Objective Validation Jun 24, 2025 Xiao Yu, Yidan Zhang, Hui Wang Journal Article |
 European Archives Of Oto-rhino-laryngology : Official Journal Of The European - Volume 282 Issue 7, Page 3629-3635Surgical interventions for empty nose syndrome: A meta-analysis of meta-analyses Jun 3, 2025 Leire Aguirre-Peña, Octavio Garaycochea, Isam Alobid, Holger Sudhoff, Manuel Bernal-Sprekelsen INTRODUCTION: Empty nose syndrome (ENS) is a complex iatrogenic condition resulting from excessive inferior turbinate resection, leading to paradoxical nasal obstruction despite an objectively patent ... Journal Article |
 Powder Technology - Volume 458, 31 May 2025Approaching particle deposition separation characteristics in the Empty Nose Syndrome (ENS) nasal cavities with CT image-based nasal cavity and CFD-DPM simulations May 31, 2025 Implant improves deposition in ENS side by optimizing surface area and vortex. Journal Article |
 International Forum Of Allergy & Rhinology - Volume 15 Issue 11, Page 1209-1216Postoperative Sleep Outcomes in Empty Nose Syndrome: Associations With Psychiatric Symptomatology May 30, 2025 Hsiang-An Hsueh, Ta-Jen Lee, Li-Pang Chuang, Chi-Che Huang, Yi-Wei Chen, Po-Hung Chang, Chia-Chen Wu, Ya-Cheng Tang, Chia-Hsiang Fu Download This study demonstrated significant subjective improvements in sleep quality and daytime sleepiness in patients with ENS after reconstructive surgery Journal Article |
 International Forum Of Allergy & Rhinology - Volume 15 Issue 9, Page 993-996Association Between Autonomic Dysfunction and Empty Nose Syndrome May 30, 2025 Cheng-Yu Li, Ta-Jen Lee, Yi-Wei Chen, Po-Hung Chang, Ya-Cheng Tang, Yu-Chieh Chen, Shu-Yen Wan, Chia-Hsiang Fu Findings demonstrate a significant association between ENS and autonomic dysfunction, with more severe cases of ENS presenting with a greater degree of autonomic dysfunction. Journal Article |
 ASAN Medical CenterAiming to Help Empty Nose Syndrome Patients in Oman With Newly Acquired Surgical Skills May 7, 2025 I had the opportunity to learn the ENS surgery technique firsthand, which I had only heard about. Empty Nose Syndrome (ENS) occurs when excessive space in the nasal cavity leads to dryness, irritat... News Story Testimonial |
