Empty Nose Syndrome (ENS) Research & Patient Resource

Airflow Characteristics of Empty Nose Syndrome: Insights From Patient-Specific Computational Modeling of Airflow Distribution Patterns and Nasal Air-Conditioning

BACKGROUND: Computational fluid dynamics (CFD) is increasingly used to investigate the complex pathophysiology of empty nose syndrome (ENS). Although previous CFD studies reported middle-meatus-dominant airflow and reduc...

In Response to Cluster Analysis of Patients With Empty Nose Syndrome and Its Relation to Surgical Outcome

In Reference to "Cluster Analysis of Patients With Empty Nose Syndrome and Its Relation to Surgical Outcome"

Inferior Turbinate Preservation Surgery: Surgical Strategies to Prevent Empty Nose Syndrome

BACKGROUND: Inferior turbinate hypertrophy is one of the leading causes of chronic nasal obstruction and represents a frequent challenge in nasal surgical practice. Surgical management of this condition should aim not on...

Clinical Efficacy of Topical Nitroglycerin Ointment for Patients With Empty Nose Syndrome

OBJECTIVES: The objective of this study was to assess the clinical efficacy and safety of topical nitroglycerin ointment in patients diagnosed with empty nose syndrome (ENS). METHODS: ENS was diagnosed based on clinical ...

Empty Nose Syndrome in Granulomatosis Polyangiitis

Italian validation of the ENS6Q: a disease-specific questionnaire for empty nose syndrome

Empty Nose Syndrome: An Update on Pathophysiology, Diagnosis, and Treatment

Empty nose syndrome (ENS) is a chronic sinonasal condition that typically results from overly aggressive turbinate reduction. It is characterized by nasal dryness, crusting, burning sensation, and a paradoxical perceptio...

RePER reviews coding of ENS: a key step in its recognition in Spain

The Spanish Association of Empty Nose Syndrome (AESNV) shares an update on the process initiated in December 2025 for the review of the coding of Empty Nose Syndrome (SNV) in the RePER.

Anatomical Empty Nose in Dogs and Cats After Nasal Disease or Endoscopic Endonasal Surgery: Implications for Human Empty Nose Syndrome?

An objective and anatomical empty nose refers to severe turbinate destruction and can be observed in dogs and cats following nasal diseases or surgical interventions, as evidenced on computed tomography and rhinoscopy. I...

Does Total Inferior and Middle Turbinectomy Always Lead to Empty Nose Syndrome?

OBJECTIVE: Empty Nose Syndrome (ENS) is a rare and paradoxical complication often associated with aggressive turbinate reductions. Previous computational fluid dynamic (CFD) modeling has indicated that distorted nasal ai...

Three-year outcomes of posterior nasal neurectomy for allergic rhinitis: Clinical outcomes by surgical technique with a focus on ENS-related symptoms

OBJECTIVE: This study aimed to evaluate the 3-year outcomes of submucous inferior turbinectomy combined with posterior nasal neurectomy (PNN) in patients with allergic rhinitis and explore empty nose syndrome (ENS)-relat...

Evidence-based approaches for Empty Nose Syndrome management: a systematic review highlighting current treatments and future directions

It is crucial to identify potential ENS patient subgroups based on the underlying injury type driving symptoms. Such stratification would guide the selection of the most appropriate therapy

Nasal Septal Perforation: A Potential Pitfall in Cotton Testing for Suspected Empty Nose Syndrome-A Case Series and Staged Algorithm

Cluster Analysis of Patients With Empty Nose Syndrome and Its Relation to Surgical Outcome

Patients with empty nose syndrome (ENS) present heterogeneous symptom patterns and varied surgical outcomes. This study aimed to stratify patients with ENS based on preoperative 25-item Sinonasal Outcome Test (SNOT-25) s...

Empty Nose Syndrome Treated With Inferior Turbinate Augmentation Using Homologous Costal Cartilage

Empty nose syndrome (ENS) is a debilitating, iatrogenic condition caused by a previous inferior turbinectomy; the symptoms of which include subjective feelings of suffocation despite an objectively patent nasal passage. ...

Nasal Air-Jet Sensitivity Differentiates Empty Nose Syndrome and Turbinate Reduction Patients: A Pilot Study

Abnormal nasal mucosal function has been frequently implicated in the symptomatology of empty nose syndrome (ENS), yet with limited evidence. This prospective pilot study aims to compare nasal mucosal sensitivity to air-...

Validity and Reliability of a French Version of the Empty Nose Syndrome 6-Item Questionnaire

To validate a French version of the Empty Nose Syndrome 6-Item Questionnaire (Fr-ENS6Q). Methods: Thirty-three patients with a diagnosis of empty nose syndrome (ENS) and 50 healthy individuals completed the Fr-ENS6Q and ...

CPAP efficacy in sleep apnea syndrome coexisting with empty nose syndrome: A case report

Continuous positive airway pressure (CPAP) therapy was initiated and found to be effective. CPAP therapy may be beneficial when SAS complicates ENS, even with a capacious nasal airway.

Serpentine Sign: evidence of airway compensation in patients with empty nose syndrome

This study aimed to evaluate the presence of Serpentine Signs on computed tomography (CT) images and its impact on the clinical symptoms in patients with empty nose syndrome (ENS). METHODS: A retrospective study analysed...