| The Laryngoscope Clinical Efficacy of Topical Nitroglycerin Ointment for Patients With Empty Nose Syndrome Jun 5, 2026 Sung Seok Ryu, Sohee Kang, Yong-ju Jang OBJECTIVES: The objective of this study was to assess the clinical efficacy and safety of topical nitroglycerin ointment in patients diagnosed with empty nose syndrome (ENS). METHODS: ENS was diagnose... Journal Article |
| Clinical And Experimental Otorhinolaryngology Empty Nose Syndrome: An Update on Pathophysiology, Diagnosis, and Treatment Jun 1, 2026 Ziang Gao, Yong-Ju Jang Empty nose syndrome (ENS) is a chronic sinonasal condition that typically results from overly aggressive turbinate reduction. It is characterized by nasal dryness, crusting, burning sensation, and a p... Journal Article |
| Acta Otorhinolaryngologica Italica : Organo Ufficiale Della Societa Italiana Di - Volume 46 Issue 3, Page 246-248 Italian validation of the ENS6Q: a disease-specific questionnaire for empty nose syndrome Jun 1, 2026 Matteo Alicandri-Ciufelli, Luigi Raguso, Sofia Passaseo, Graziella Pellegrini, Davide Adamo, Giulia Galaverni, Gian Maria Galeazzi, Daniele Marchioni, Daniela Lucidi, Luca Pingani Journal Article |
 Spanish Association of Empty Nose SyndromeRePER reviews coding of ENS: a key step in its recognition in Spain [Spanish - Translate] May 26, 2026 The Spanish Association of Empty Nose Syndrome (AESNV) shares an update on the process initiated in December 2025 for the review of the coding of Empty Nose Syndrome (SNV) in the RePER. |
| Otolaryngology--head And Neck Surgery : Official Journal Of American Academy Of - Volume 175 Issue 1, Page 71-77 Does Total Inferior and Middle Turbinectomy Always Lead to Empty Nose Syndrome? May 5, 2026 Nidhi Jha, Jed Speers, Ahmad Odeh, Zhenxing Wu, James Mihalich, Lauren E Gastineau, Bradley Hittle, Bradley A Otto, Kathleen M Kelly, Gregory J Wiet, Kai Zhao OBJECTIVE: Empty Nose Syndrome (ENS) is a rare and paradoxical complication often associated with aggressive turbinate reductions. Previous computational fluid dynamic (CFD) modeling has indicated tha... Journal Article |
| American Journal Of Otolaryngology - Volume 47 Issue 4, Page 104852 Three-year outcomes of posterior nasal neurectomy for allergic rhinitis: Clinical outcomes by surgical technique with a focus on ENS-related symptoms Apr 28, 2026 Momoko Takeda, Hiroshi Utsunomiya, Toshio Miki OBJECTIVE: This study aimed to evaluate the 3-year outcomes of submucous inferior turbinectomy combined with posterior nasal neurectomy (PNN) in patients with allergic rhinitis and explore empty nose ... Journal Article |
 Frontiers In Bioengineering And Biotechnology - Volume 14 , Page 1778266Evidence-based approaches for Empty Nose Syndrome management: a systematic review highlighting current treatments and future directions Apr 8, 2026 Giulia Galaverni, Davide Adamo, Anjana Chathanchirappattu Raj, Vincenzo Giuseppe Genna, Graziella Pellegrini It is crucial to identify potential ENS patient subgroups based on the underlying injury type driving symptoms. Such stratification would guide the selection of the most appropriate therapy Journal Article |
 International Forum Of Allergy & Rhinology - Volume 16 Issue 4, Page 426-428Nasal Septal Perforation: A Potential Pitfall in Cotton Testing for Suspected Empty Nose Syndrome-A Case Series and Staged Algorithm Mar 11, 2026 Yu Hosokawa, Takayuki Kawamoto, Masafumi Sawada, Momotaro Harano, Motohiro Sato, Rena Kobayashi, Tetsuo Ikezono Journal Article |
 The Laryngoscope - Volume 136 Issue 8, Page 3391-3397Cluster Analysis of Patients With Empty Nose Syndrome and Its Relation to Surgical Outcome Feb 26, 2026 Chia-Hsin Lu, Yun-Shien Lee, Pei-Wen Wu, Chi-Che Huang, Po-Hung Chang, Ta-Jen Lee, Chien-Chia Huang Patients with empty nose syndrome (ENS) present heterogeneous symptom patterns and varied surgical outcomes. This study aimed to stratify patients with ENS based on preoperative 25-item Sinonasal Outc... Journal Article |
 Plastic And Reconstructive Surgery. Global Open - Volume 14 Issue 2, Page e7466Empty Nose Syndrome Treated With Inferior Turbinate Augmentation Using Homologous Costal Cartilage Feb 25, 2026 Yu-Hsun Chiu, Chung-Yu Hao, Yu-Xiang Kuo, Wei-Li Hung Empty nose syndrome (ENS) is a debilitating, iatrogenic condition caused by a previous inferior turbinectomy; the symptoms of which include subjective feelings of suffocation despite an objectively pa... Journal Article |
 The Laryngoscope - Volume 136 Issue 6, Page 2491-2498Nasal Air-Jet Sensitivity Differentiates Empty Nose Syndrome and Turbinate Reduction Patients: A Pilot Study Jan 31, 2026 Kanghyun Kim, Ahmad Odeh, Jack Harness, Nidhi Jha, Veronica Formanek, Joseph Lee, Bradley Otto, Kathleen Kelly, Kai Zhao Abnormal nasal mucosal function has been frequently implicated in the symptomatology of empty nose syndrome (ENS), yet with limited evidence. This prospective pilot study aims to compare nasal mucosal... Journal Article |
 Journal Of Clinical Medicine - Volume 15 Issue 2Validity and Reliability of a French Version of the Empty Nose Syndrome 6-Item Questionnaire Jan 19, 2026 Antonino Maniaci, Jérôme R Lechien To validate a French version of the Empty Nose Syndrome 6-Item Questionnaire (Fr-ENS6Q). Methods: Thirty-three patients with a diagnosis of empty nose syndrome (ENS) and 50 healthy individuals complet... Journal Article |
 Acta Oto-LaryngologicaCPAP efficacy in sleep apnea syndrome coexisting with empty nose syndrome: A case report Jan 3, 2026 Continuous positive airway pressure (CPAP) therapy was initiated and found to be effective. CPAP therapy may be beneficial when SAS complicates ENS, even with a capacious nasal airway. Case Report Journal Article |
| Rhinology - Volume 63 Issue 6, Page 736-743 Serpentine Sign: evidence of airway compensation in patients with empty nose syndrome Dec 1, 2025 P-W Wu, F T-N Yu, T-J Lee, C-C Huang, P-H Chang, C-C Huang This study aimed to evaluate the presence of Serpentine Signs on computed tomography (CT) images and its impact on the clinical symptoms in patients with empty nose syndrome (ENS). METHODS: A retrospe... Journal Article |
 Journal Of Rhinology : Official Journal Of The Korean Rhinologic Society - Volume 32 Issue 3, Page 162-168Assessment of Autonomic Dysfunction in Patients With Empty Nose Syndrome Using the Composite Autonomic Symptom Scale-31 Nov 27, 2025 Sung Seok Ryu, Do Yeon Kim, Yong-ju Jang BACKGROUND AND OBJECTIVES: Empty nose syndrome (ENS) can occur as a consequence of aggressive turbinate surgery. However, some patients with similar surgical histories do not develop ENS, suggesting t... Journal Article |
 Journal Of Rhinology : Official Journal Of The Korean Rhinologic Society - Volume 32 Issue 3, Page 175-183Optimizing Human Nasal Turbinate Stem Cell Dosage for the Effective Treatment of Empty Nose Syndrome Nov 27, 2025 Yun Jin Kang, Dan Bi Park, David W Jang, Mi Hyun Lim, Jae Yoon Lee, Seung Yeon Yoo, Sung Won Kim, Do Hyun Kim BACKGROUND AND OBJECTIVES: Empty nose syndrome (ENS) is a chronic and debilitating condition characterized by atrophic nasal mucosa and impaired mucosal function, resulting in persistent nasal discomf... Journal Article |
 A Physiological Explanation of Stress, Air Hunger and Autonomic DysregulationNov 20, 2025 ENS disrupts multiple interlinked systems — nasal mechanics and sensation, lung reflexes, CO? balance, baroreflex function, cardiac rhythm and higher brain regulation — producing a predictable physiol... Blog |
 Stanford UniversityPersonalized Sound Therapy Study for Empty Nose Syndrome Treatment Oct 3, 2025 Kai Zhao Stanford University researchers are conducting a groundbreaking clinical trial investigating acoustic resonance therapy (ART) for ENS Research |
| Indian Journal Of Otolaryngology And Head And Neck Surgery : Official Publication - Volume 77 Issue 11, Page 5290 Correction to: From Dry Cavities to Healing Pathways: Innovations in Managing Empty Nose Syndrome Sep 18, 2025 Surbhi, Atul Anand, Vineet Sinha [This corrects the article DOI: 10.1007/s12070-025-05445-0.]. Journal Article |
 ENT IstambulThe Discrepancy Between Turbinate Size and Patient Complaints in Empty Nose Syndrome Sep 15, 2025 Murat Enöz Turbinate Volume May Be Large, but Functionally Decreased. The health of the outer mucosa of the turbinates is crucial. |
